Which call method is the fastest?

Which call method is fastest?

Method 1

Sub Macro1
pseudo code
Call Macro2
Exit Sub

Method 2

Sub Macro1
pseudo code
Macro2
Exit Sub

Method 3

Sub Macro1
pseudo code
Application.Run "Macro2"
Exit Sub

(If there is a speed difference but the difference is negligible then, just for the sake of the argument, imagine the code is running on a very slow computer).

Also apart from code appearance & speed difference (if any) are there any pros/cons to any of these methods?