Is it good idea to run large VBA program in OneDrive?

I tend to save macro-enable workbook in local hard drive, since I believe that it will run much faster in local hard drive.

How about running the program when file is saved in OneDrive? Does it slow down a lot?

I don't really use OneDrive before, if I install OneDrive in every PC, does it make difference if you run macro in OneDrive folder vs. run macro in local hard drive folder?

One good thing to store file in OneDrive: I can have most current version of file in multiple device.

Thanks.