If data matches then clear the data by vba

Hello Sir
I am looking for a macro
we have to look for only positive numbers in column S of sample1.xls & match column Y of sample1.xls with column B of sample2.xlsx
if it matches then clear all the data in that row from column C of sample2.xlsx
In the sample file
3rd row data will be cleared from Column C(we will not clear the data of column A and Column B, clearing of the data will be start from Column C)