Matching a range of values

if there are not alot of columns, I would concatenate the columns, separating each with a special symbol, in order to avoid crossovers

e.g.

=A1&"^^"&B1&"^^"&C1&"^^"&D1

copied down

then you can use Countif to find if there are dupes:

=COUNTIF($E$1:$E1,$E1)>1

copied down (where E1 contains first concatenation formula)

TRUE means there are duplicates.