Exclude specific parameters in a column while using SUMIFS

Hey guys, I have a SUMIFS function written that reads where some of my budget is coming from. I track several different departments but am only responsible for some of the departments' budgets. So i need to exclude two of the departments when the SUMIFS is reading the other parameters from my list.

From the example i attached, how would i go about writing the formula in I3 to skip the Cost if it comes from Dep 2 and Dep 4?

Thanks for the help!