Depending on how many criteria you have, you can also use a sum with multiple (up to 7) IF statements. It's a Ctrl+Shift+Enter function.
={sum(if(A1:A25="XSAS",if(A1:Z1="Region 1",A2:Z2,0),0))}
Now for the ranges, you can input whatever you want depending on how big your range is. Hope this helps!
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