Don,
Appreciate the feedback, but I can't seem to incorporate your suggestion into my code. I've tried a couple of methods. See Below.

Private Sub CommandButton4_Click()
Dim rngEntryBottomRow As Range
Dim Msg As Integer
Dim Response As Integer
Dim colIndex As Integer
Dim cnt As Integer

Application.EnableEvents = False
Application.ScreenUpdating = False

Set rngEntryBottomRow = Range("Below_Entry_Bottom_Row").Offset(-1)
cnt = 0

For colIndex = 1 To 8
With rngEntryBottomRow.Cells(0, colIndex)
If .SpecialCells(xlConstants) > 0 Then cnt = cnt + 1
'If .SpecialCells(xlConstants)= True Then cnt = cnt + 1
End With
Next colIndex

If cnt > 3 Then
Msg = MsgBox("You are attempting to Delete a Row that contains User Input." _
& " Delete Row Failed", vbOKOnly + vbCritical, "Can Not Delete Row with Information")
If Response = 1 Or 2 Then GoTo RET
End If
If cnt = 3 Then
With rngEntryBottomRow
.EntireRow.Delete
End With
End If

RET:
Application.ScreenUpdating = True
Application.EnableEvents = True
End Sub