I seem to be using this one a lot today....
Apply this UDF to your workbook (ALT+F11, Insert|Module) and then paste:
Then in B2 of Sheet1:
=SUBSTITUTE(TRIM(aconcat(IF(ISNUMBER(SEARCH(" "&Sheet2!$A$2:$A$4&" "," "&SUBSTITUTE(A2,","," ")&" ")),Sheet2!$B$1:$B$4,"")," "))," ",",")
confirmed with CTRL+SHIFT+ENTER not just ENTER
Then to Conditionally format, invoke Conditional Formatting, select New Rule, then select Use a formula to determine which cellls to format and enter formula:
=SEARCH("open",$B2)
click Format and choose colour.
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