I think you want this
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=HYPERLINK("http://www.domain.com"&A1&B1,C1)
Here are the problems with your example:
Use "&" to concatenate strings. "+" is for addition only.
If you put cell references inside quotes, they are going to be interpreted as a string.
I don't know what you're trying to do with the [brackets] but they shouldn't be there.
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